| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31694.1 | EED32226.1 | NOR53_3272 | NOR53_2965 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | [E] COG0070 Glutamate synthase domain 3. | 0.885 |
| EED31694.1 | nadE | NOR53_3272 | NOR53_149 | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.873 |
| EED32226.1 | EED31694.1 | NOR53_2965 | NOR53_3272 | [E] COG0070 Glutamate synthase domain 3. | [F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family. | 0.885 |
| EED32226.1 | EED33765.1 | NOR53_2965 | NOR53_1994 | [E] COG0070 Glutamate synthase domain 3. | P-protein; [E] COG1605 Chorismate mutase. | 0.674 |
| EED32226.1 | nadE | NOR53_2965 | NOR53_149 | [E] COG0070 Glutamate synthase domain 3. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.856 |
| EED32973.1 | EED33046.1 | NOR53_1808 | NOR53_1084 | [F] COG1051 ADP-ribose pyrophosphatase. | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | 0.621 |
| EED32973.1 | cinA | NOR53_1808 | NOR53_194 | [F] COG1051 ADP-ribose pyrophosphatase. | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.797 |
| EED32973.1 | nadC | NOR53_1808 | NOR53_1107 | [F] COG1051 ADP-ribose pyrophosphatase. | Nicotinate-nucleotide diphosphorylase (carboxylating); [H] COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.647 |
| EED32973.1 | nadD | NOR53_1808 | NOR53_2825 | [F] COG1051 ADP-ribose pyrophosphatase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.666 |
| EED32973.1 | nadE | NOR53_1808 | NOR53_149 | [F] COG1051 ADP-ribose pyrophosphatase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.875 |
| EED32973.1 | nadK | NOR53_1808 | NOR53_2386 | [F] COG1051 ADP-ribose pyrophosphatase. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.647 |
| EED33046.1 | EED32973.1 | NOR53_1084 | NOR53_1808 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | [F] COG1051 ADP-ribose pyrophosphatase. | 0.621 |
| EED33046.1 | cinA | NOR53_1084 | NOR53_194 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.461 |
| EED33046.1 | nadD | NOR53_1084 | NOR53_2825 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.610 |
| EED33046.1 | nadE | NOR53_1084 | NOR53_149 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.833 |
| EED33046.1 | nadK | NOR53_1084 | NOR53_2386 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.565 |
| EED33765.1 | EED32226.1 | NOR53_1994 | NOR53_2965 | P-protein; [E] COG1605 Chorismate mutase. | [E] COG0070 Glutamate synthase domain 3. | 0.674 |
| EED33765.1 | nadE | NOR53_1994 | NOR53_149 | P-protein; [E] COG1605 Chorismate mutase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.836 |
| cinA | EED32973.1 | NOR53_194 | NOR53_1808 | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | [F] COG1051 ADP-ribose pyrophosphatase. | 0.797 |
| cinA | EED33046.1 | NOR53_194 | NOR53_1084 | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | 0.461 |