Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED33520.1Putative threonine dehydratase biosynthetic; [E] COG0498 Threonine synthase. (326 aa)    
Predicted Functional Partners:
ilvN
[E] COG0440 Acetolactate synthase, small (regulatory) subunit.
  
 0.861
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 0.839
NOR53_686
YeeE/YedE; [R] COG2391 Predicted transporter component.
  
    0.784
NOR53_764
Gene II and x protein; [R] COG2391 Predicted transporter component.
  
    0.776
EED31664.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
    
 0.736
ilvB_2
Acetolactate synthase, large subunit, biosynthetic type; [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].
  
 0.729
alsS
Acetolactate synthase, catabolic; [R] COG3960 Glyoxylate carboligase; Belongs to the TPP enzyme family.
  
 0.729
EED33256.1
Thiamine pyrophosphate enzyme domain protein TPP-binding protein; [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].
  
 0.729
ilvB_3
Acetolactate synthase, large subunit, biosynthetic type; [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].
  
 0.729
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
  
 
 0.721
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (10%) [HD]