STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureFUrease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (219 aa)    
Predicted Functional Partners:
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.998
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.998
ureC
Urease, alpha subunit; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.
 
 
 0.996
ureE
Dual specificity protein phosphatase; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.996
ureA
Urease, gamma subunit; [E] COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.
 
 
 0.992
ureB
Urease, beta subunit; [E] COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.
 
 
 0.986
urtC
Urea ABC transporter, permease protein UrtC; [G] COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.
 
   
 0.686
EED33458.1
Inner-membrane translocator; [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.685
xdhB
Xanthine dehydrogenase, molybdopterin binding subunit; [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.
  
    0.665
EED33459.1
[E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.
 
   
 0.663
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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