Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32830.1Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (100 aa)    
Predicted Functional Partners:
cbpA
curved-DNA-binding protein, DnaJ family; [O] COG2214 DnaJ-class molecular chaperone.
 
 
 0.992
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
    
 0.798
dnaX
DNA polymerase III, tau and gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
  0.640
holA
[L] COG1466 DNA polymerase III, delta subunit.
  
  
  0.608
EED32335.1
Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef.
    
 0.608
NOR53_724
Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef.
    
 0.608
EED33454.1
Putative Phosphate acetyl/butyryl transferase subfamily; [C] COG0281 Malic enzyme.
    
  0.606
EED32828.1
Sensory transduction histidine kinase; [T] COG2202 FOG: PAS/PAC domain.
   
 0.556
NOR53_376
Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
  0.556
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
     
  0.552
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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