Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED34028.1Conserved hypothetical protein; [S] COG3016 Uncharacterized iron-regulated protein. (284 aa)    
Predicted Functional Partners:
napA_2
[P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.
       0.634
EED32287.1
Conserved hypothetical protein.
  
     0.568
EED31952.1
Transcriptional regulator, MarR family; [K] COG1846 Transcriptional regulators.
  
     0.529
EED32627.1
Hemin import ATP-binding protein HmuV; [G] COG1129 ABC-type sugar transport system, ATPase component.
  
  
 0.524
NOR53_798
Putative rhodanese domain protein; [R] COG2391 Predicted transporter component.
  
  
  0.509
EED33480.1
Glutamate-cysteine ligase, family 2; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
  0.505
EED34030.1
Conserved hypothetical protein.
 
     0.485
EED34027.1
Carboxylesterase 1; [R] COG0400 Predicted esterase.
       0.482
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.467
EED33167.1
[M] COG1794 Aspartate racemase.
     
  0.453
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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