Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_157Transcriptional Regulator, MerR family; [K] COG0789 Predicted transcriptional regulators. (138 aa)    
Predicted Functional Partners:
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
    
 0.856
NOR53_50
hydroxymethylglutaryl-CoA lyase; [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases.
 
 
 0.839
NOR53_213
methylcrotonoyl-CoA carboxylase subunit alpha; [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase).
  
 0.831
NOR53_135
[I] COG1960 Acyl-CoA dehydrogenases.
 
    0.764
NOR53_294
methylcrotonoyl-CoA carboxylase beta chain; [I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
  
  
 0.758
EED33454.1
Putative Phosphate acetyl/butyryl transferase subfamily; [C] COG0281 Malic enzyme.
    
 0.756
dnaX
DNA polymerase III, tau and gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
  0.753
EED31684.1
Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase.
   
 0.749
NOR53_376
Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
  0.739
EED32335.1
Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef.
    
 0.719
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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