Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32508.1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (368 aa)    
Predicted Functional Partners:
fghA
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
 0.999
EED31424.1
[C] COG1454 Alcohol dehydrogenase, class IV.
    
 0.839
NOR53_327
Putative maleylacetate reductase; [C] COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family.
    
 0.839
EED31791.1
[C] COG1454 Alcohol dehydrogenase, class IV.
    
 0.839
mxaF
Methanol dehydrogenase protein, large subunit; [C] COG2010 Cytochrome c, mono- and diheme variants.
    
 0.747
NOR53_636
Alcohol dehydrogenase (acceptor); [S] COG1520 FOG: WD40-like repeat.
    
 0.747
cdd
[FJ] COG0590 Cytosine/adenosine deaminases.
  
 
  0.734
tadA
tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
 
  0.734
EED32103.1
Alkane 1-monooxygenase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
 0.667
msbA
Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
   
  0.649
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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