EED33081.1 protein (gamma proteobacterium NOR53)

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EED33081.1

Phage integrase; [L] COG4974 Site-specific recombinase XerD. (208 aa)

Predicted Functional Partners:

ruvB

0.694

uvrB

0.688

ruvA

0.685

rnpA

0.684

ruvC

0.676

uvrA

0.650

NOR53_449

0.623

uvrC

0.587

cho

0.587

xerD

0.577

Your Current Organism:

gamma proteobacterium NOR53

NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EED33081.1	NOR53_449	NOR53_1586	NOR53_449	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	0.623
EED33081.1	cho	NOR53_1586	NOR53_3383	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	[L] COG0322 Nuclease subunit of the excinuclease complex.	0.587
EED33081.1	rnpA	NOR53_1586	NOR53_3540	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	0.684
EED33081.1	ruvA	NOR53_1586	NOR53_2734	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	0.685
EED33081.1	ruvB	NOR53_1586	NOR53_2531	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.	0.694
EED33081.1	ruvC	NOR53_1586	NOR53_2783	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.	0.676
EED33081.1	uvrA	NOR53_1586	NOR53_123	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.	0.650
EED33081.1	uvrB	NOR53_1586	NOR53_2128	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]	0.688
EED33081.1	uvrC	NOR53_1586	NOR53_1885	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.	0.587
EED33081.1	xerD	NOR53_1586	NOR53_2052	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.	0.577
NOR53_449	EED33081.1	NOR53_449	NOR53_1586	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	Phage integrase; [L] COG4974 Site-specific recombinase XerD.	0.623
NOR53_449	cho	NOR53_449	NOR53_3383	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	[L] COG0322 Nuclease subunit of the excinuclease complex.	0.771
NOR53_449	rnpA	NOR53_449	NOR53_3540	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	0.816
NOR53_449	ruvA	NOR53_449	NOR53_2734	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	0.810
NOR53_449	ruvB	NOR53_449	NOR53_2531	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.	0.818
NOR53_449	ruvC	NOR53_449	NOR53_2783	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.	0.812
NOR53_449	uvrA	NOR53_449	NOR53_123	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.	0.810
NOR53_449	uvrB	NOR53_449	NOR53_2128	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]	0.818
NOR53_449	uvrC	NOR53_449	NOR53_1885	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.	0.764
NOR53_449	xerD	NOR53_449	NOR53_2052	Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.	Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.	0.627