Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureAUrease, gamma subunit; [E] COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. (104 aa)    
Predicted Functional Partners:
ureB
Urease, beta subunit; [E] COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.
 0.999
ureC
Urease, alpha subunit; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.
 0.999
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.991
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.984
ureE
Dual specificity protein phosphatase; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.958
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.941
allC
[F] COG4266 Allantoicase; Belongs to the allantoicase family.
    
  0.798
allA
[F] COG3194 Ureidoglycolate hydrolase.
    
  0.787
uraD
OHCU decarboxylase; [S] COG3195 Uncharacterized protein conserved in bacteria.
    
  0.716
EED33436.1
Fumarylacetoacetate hydrolase; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
     
  0.647
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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