STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phoUPhosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake. (240 aa)    
Predicted Functional Partners:
pstA
Phosphate ABC transporter, permease protein PstA; [P] COG4208 ABC-type sulfate transport system, permease component.
 
  
 0.998
pstS
ABC superfamily (peri_bind) high-affinity phosphate transporter; [P] COG0226 ABC-type phosphate transport system, periplasmic component.
 
  
 0.915
NOR53_703
Binding-protein-dependent transport systems inner membrane component; [P] COG0581 ABC-type phosphate transport system, permease component.
 
  
 0.861
hisC
[E] COG0436 Aspartate/tyrosine/aromatic aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
       0.783
EED33350.1
YaeQ; [S] COG4681 Uncharacterized protein conserved in bacteria.
   
    0.760
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.682
phoR
Phosphate regulon sensor kinase PhoR; [T] COG0642 Signal transduction histidine kinase.
 
   
 0.643
lepB
[U] COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
  
    0.505
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.503
EED32586.1
Adenylate cyclase 1 (ATP pyrophosphate-lyase 1); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
  
  
 0.483
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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