EED33076.1 protein (gamma proteobacterium NOR53)

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EED33076.1

Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. (249 aa)

Predicted Functional Partners:

mtaD

0.804

NOR53_18

0.802

EED33077.1

0.792

NOR53_390

0.684

xdhB

0.663

EED31377.1

0.662

EED31790.1

0.660

NOR53_399

0.659

soxB

0.658

adeC

0.649

Your Current Organism:

gamma proteobacterium NOR53

NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EED31377.1	EED33076.1	NOR53_2770	NOR53_1639	Decarboxylase family protein; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein.	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	0.662
EED31377.1	NOR53_390	NOR53_2770	NOR53_390	Decarboxylase family protein; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein.	HAD-superfamily hydrolase subfamily IA, variant 3; [R] COG0637 Predicted phosphatase/phosphohexomutase.	0.405
EED31377.1	NOR53_399	NOR53_2770	NOR53_399	Decarboxylase family protein; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein.	[S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.	0.647
EED31377.1	adeC	NOR53_2770	NOR53_672	Decarboxylase family protein; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein.	[F] COG1001 Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.	0.647
EED31377.1	soxB	NOR53_2770	NOR53_2972	Decarboxylase family protein; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein.	Sulfur oxidation protein SoxB; [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.	0.647
EED31790.1	EED33076.1	NOR53_3593	NOR53_1639	Alpha/beta hydrolase fold-3 domain protein; [I] COG0657 Esterase/lipase.	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	0.660
EED33076.1	EED31377.1	NOR53_1639	NOR53_2770	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	Decarboxylase family protein; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein.	0.662
EED33076.1	EED31790.1	NOR53_1639	NOR53_3593	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	Alpha/beta hydrolase fold-3 domain protein; [I] COG0657 Esterase/lipase.	0.660
EED33076.1	EED33077.1	NOR53_1639	NOR53_1399	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	[M] COG0668 Small-conductance mechanosensitive channel.	0.792
EED33076.1	NOR53_18	NOR53_1639	NOR53_18	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	Hypothetical protein; [R] COG1073 Hydrolases of the alpha/beta superfamily.	0.802
EED33076.1	NOR53_390	NOR53_1639	NOR53_390	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	HAD-superfamily hydrolase subfamily IA, variant 3; [R] COG0637 Predicted phosphatase/phosphohexomutase.	0.684
EED33076.1	NOR53_399	NOR53_1639	NOR53_399	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	[S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.	0.659
EED33076.1	adeC	NOR53_1639	NOR53_672	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	[F] COG1001 Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.	0.649
EED33076.1	mtaD	NOR53_1639	NOR53_1983	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.	0.804
EED33076.1	soxB	NOR53_1639	NOR53_2972	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	Sulfur oxidation protein SoxB; [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.	0.658
EED33076.1	xdhB	NOR53_1639	NOR53_1221	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	Xanthine dehydrogenase, molybdopterin binding subunit; [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.	0.663
EED33077.1	EED33076.1	NOR53_1399	NOR53_1639	[M] COG0668 Small-conductance mechanosensitive channel.	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	0.792
NOR53_18	EED33076.1	NOR53_18	NOR53_1639	Hypothetical protein; [R] COG1073 Hydrolases of the alpha/beta superfamily.	Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.	0.802
NOR53_18	NOR53_399	NOR53_18	NOR53_399	Hypothetical protein; [R] COG1073 Hydrolases of the alpha/beta superfamily.	[S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.	0.760
NOR53_18	soxB	NOR53_18	NOR53_2972	Hypothetical protein; [R] COG1073 Hydrolases of the alpha/beta superfamily.	Sulfur oxidation protein SoxB; [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.	0.753

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