Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EED32656.1Conserved hypothetical protein. (288 aa)    
Predicted Functional Partners:
nhaA
Na+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
   
    0.833
rdgB
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.795
NOR53_776
General secretion pathway protein A; [U] COG3267 Type II secretory pathway, component ExeA (predicted ATPase).
  
    0.705
EED32518.1
Transporter; [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
     
  0.544
EED32517.1
Von Willebrand factor, type A; [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
     
  0.544
EED33197.1
TPR repeat-containing protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
  0.544
EED33833.1
Hypothetical protein.
     
  0.544
EED33953.1
Sulfotransferase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
  0.544
EED31194.1
Sulfotransferase; [R] COG0457 FOG: TPR repeat.
     
  0.544
EED31857.1
Tetratricopeptide TPR_2; [R] COG0457 FOG: TPR repeat.
     
  0.544
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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