Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
maiA_2Maleylacetoacetate isomerase; [O] COG0625 Glutathione S-transferase. (213 aa)    
Predicted Functional Partners:
hmgA
[Q] COG3508 Homogentisate 1,2-dioxygenase.
 
 
 0.993
NOR53_7
[Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
 
 
 0.973
hppD
[ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.
 
 
 0.954
EED33379.1
Fumarylacetoacetate hydrolase; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
 
 
 0.933
NOR53_414
Transcriptional regulator, MarR family; [K] COG1846 Transcriptional regulators.
 
     0.827
EED33865.1
glutamyl-tRNA(Gln) amidotransferase C subunit; [O] COG0625 Glutathione S-transferase.
  
 
 
 0.814
NOR53_188
[E] COG3186 Phenylalanine-4-hydroxylase.
 
  
 0.791
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.787
mhbB
Fumarylpyruvate hydrolase; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
  
 
 0.744
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.705
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.