Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED32502.1Alcohol dehydrogenase, zinc-binding domain protein; [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (329 aa)    
Predicted Functional Partners:
NOR53_868
[QP] COG4242 Cyanophycinase and related exopeptidases; Belongs to the peptidase S51 family.
       0.774
EED32501.1
Nucleoside recognition domain protein; [S] COG3314 Uncharacterized protein conserved in bacteria.
       0.741
EED32733.1
6-phosphogluconate dehydrogenase, NAD-binding; [G] COG0362 6-phosphogluconate dehydrogenase.
  
  
  0.703
NOR53_826
4-hydroxybutyrate coenzyme A transferase; [C] COG0427 Acetyl-CoA hydrolase.
  
 
  0.695
fadJ
Fatty acid oxidation complex, alpha subunit; [I] COG1250 3-hydroxyacyl-CoA dehydrogenase.
  
 0.674
gltA
[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.
   
  0.674
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.664
EED33695.1
Putative aminotransferase class III (putative 4-aminobutyrate aminotransferase); [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.647
mmsB
[G] COG1023 Predicted 6-phosphogluconate dehydrogenase; Belongs to the HIBADH-related family.
     
  0.647
fadB
Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 0.613
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (22%) [HD]