STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED32489.1[C] COG0778 Nitroreductase. (224 aa)    
Predicted Functional Partners:
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
    
 0.755
birA
biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.713
NOR53_899
Nitrilotriacetate monooxygenase component B; [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.
  
 
  0.676
EED32253.1
Oxidoreductase, zinc-binding dehydrogenase family; [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.
  
     0.612
EED32833.1
[V] COG0842 ABC-type multidrug transport system, permease component.
  
  
 0.566
NOR53_928
Antibiotic biosynthesis monooxygenase domain protein; [S] COG1359 Uncharacterized conserved protein.
 
 
  0.566
EED31607.1
Glyoxalase/bleomycin resistance protein/dioxygenase.
  
    0.551
EED33531.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.549
EED32115.1
Putative glyoxalase/bleomycin resistance protein/dioxygenase; [E] COG0346 Lactoylglutathione lyase and related lyases.
  
    0.547
EED34057.1
[S] COG5470 Uncharacterized conserved protein.
  
     0.543
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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