Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32718.1ATPase; [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. (482 aa)    
Predicted Functional Partners:
EED32715.1
Anti-sigma factor MucA; [T] COG3073 Negative regulator of sigma E activity.
  
 
 0.845
lepB
[U] COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
 
  
 0.792
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
    
 0.741
EED32717.1
Positive regulator for alginate biosynthesis MucC; [T] COG3086 Positive regulator of sigma E activity.
  
  
 0.694
EED32716.1
Putative negative regulator for alginate biosynthesis; [T] COG3026 Negative regulator of sigma E activity.
  
  
 0.639
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
  
 0.537
EED31574.1
[O] COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1.
  
 
 0.524
rseP
RIP metalloprotease RseP; [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1.
 
  
 0.505
rplY
Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
 
   0.486
EED32755.1
PspC domain family protein; [KT] COG1983 Putative stress-responsive transcriptional regulator.
   
  
 0.452
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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