Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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cobOcob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (203 aa)    
Predicted Functional Partners:
bchH
Magnesium chelatase, H subunit; [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.
 
 
 0.838
NOR53_721
[P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
  
  
 0.836
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
    
 0.800
EED32627.1
Hemin import ATP-binding protein HmuV; [G] COG1129 ABC-type sugar transport system, ATPase component.
       0.799
hmuU
Hemin ABC transporter, permease protein; [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
     
 0.793
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.673
EED33981.1
Hemin import ATP-binding protein HmuV; [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.
    
  0.618
EED33052.1
[E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.
    
 0.517
hisC
[E] COG0436 Aspartate/tyrosine/aromatic aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
    
 0.517
EED32900.1
[I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).
 
   
 0.503
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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