Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dhlAHaloalkane dehalogenase; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (337 aa)    
Predicted Functional Partners:
NOR53_18
Hypothetical protein; [R] COG1073 Hydrolases of the alpha/beta superfamily.
    
 0.686
EED33391.1
Ribonuclease Z; [R] COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III.
 
     0.681
NOR53_858
NAD-dependent epimerase/dehydratase; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases.
  
  
 0.602
EED31450.1
Hypothetical protein; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold.
  
     0.592
sucA
[C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
    
  0.565
NOR53_958
AMP-ligase; [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 0.545
EED32508.1
S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
    
  0.542
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
   
  0.535
fabH
[I] COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III.
 
  
 0.530
EED34003.1
Sulfide dehydrogenase (flavocytochrome c) flavoprotein chain; [C] COG1252 NADH dehydrogenase, FAD-containing subunit.
    
  0.528
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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