Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hutZHeme-binding protein HutZ; [P] COG0748 Putative heme iron utilization protein. (176 aa)    
Predicted Functional Partners:
EED33985.1
Conserved hypothetical protein; [P] COG3721 Putative heme iron utilization protein.
 
  
 0.968
EED33984.1
TonB-dependent heme/hemoglobin receptor family protein; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
  
  
 0.919
hmuT
Hemin ABC transporter, periplasmic hemin-binding protein; [P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.
 
  
 0.702
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.665
EED33981.1
Hemin import ATP-binding protein HmuV; [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.
 
   
 0.661
bfr
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
     
  0.647
EED33982.1
[P] COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.592
pdxJ
Pyridoxal phosphate biosynthesis protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
     
  0.500
hemN
Oxygen-independent coproporphyrinogen III oxidase; [KB] COG1243 Histone acetyltransferase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
     
 0.425
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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