STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED32513.1[R] COG2236 Predicted phosphoribosyltransferases. (189 aa)    
Predicted Functional Partners:
add_1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
  
 0.817
EED32514.1
[P] COG0659 Sulfate permease and related transporters (MFS superfamily).
       0.739
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.715
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.681
EED32528.1
[F] COG1816 Adenosine deaminase.
 
 0.504
EED32523.1
[P] COG1629 Outer membrane receptor proteins, mostly Fe transport; overlaps another CDS with the same product name.
 
     0.466
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.444
EED33147.1
S1/P1 nuclease; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
 
  0.443
EED31694.1
[F] COG0167 Dihydroorotate dehydrogenase; Belongs to the dihydroorotate dehydrogenase family.
  
 
  0.439
EED32518.1
Transporter; [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
       0.429
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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