Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_188[E] COG3186 Phenylalanine-4-hydroxylase. (540 aa)    
Predicted Functional Partners:
EED31756.1
[H] COG2154 Pterin-4a-carbinolamine dehydratase.
  
 0.961
hmgA
[Q] COG3508 Homogentisate 1,2-dioxygenase.
 
  
 0.951
hppD
[ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.
 
  
 0.918
EED33765.1
P-protein; [E] COG1605 Chorismate mutase.
     
 0.885
aspC
[E] COG1448 Aspartate/tyrosine/aromatic aminotransferase.
  
 
 0.869
maiA_2
Maleylacetoacetate isomerase; [O] COG0625 Glutathione S-transferase.
 
  
 0.791
NOR53_91
Tyrosine decarboxylase 1; [E] COG0076 Glutamate decarboxylase and related PLP-dependent proteins.
  
 0.743
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.662
NOR53_414
Transcriptional regulator, MarR family; [K] COG1846 Transcriptional regulators.
    
  0.655
ntaB
Nitrilotriacetate monooxygenase component B; [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.
    
  0.654
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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