Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32848.1[Q] COG2124 Cytochrome P450. (387 aa)    
Predicted Functional Partners:
EED32850.1
Reductive dehalogenase; [C] COG1600 Uncharacterized Fe-S protein.
  
 0.873
EED32849.1
3-oxoacyl-(acyl-carrier-protein) reductase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
  0.784
polA
DNA polymerase I superfamily protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
    
 0.678
NOR53_302
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
    
  0.626
EED32847.1
Transcriptional regulator, AraC family; [K] COG2207 AraC-type DNA-binding domain-containing proteins.
 
 
   0.622
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
    
  0.596
EED31730.1
Metallophosphoesterase; [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.
    
  0.596
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.589
EED33674.1
[I] COG0657 Esterase/lipase.
 
 0.588
EED32250.1
Type III restriction enzyme, res subunit family; [LKJ] COG0513 Superfamily II DNA and RNA helicases.
  
 
  0.583
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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