Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32603.1Cysteine desulfurase; [R] COG1103 Archaea-specific pyridoxal phosphate-dependent enzymes. (388 aa)    
Predicted Functional Partners:
yhgI
IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.991
iscR
Iron-sulfur cluster assembly transcription factor IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
  
 
 0.936
tusA
SirA protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.
   
 0.934
NOR53_165
Conserved hypothetical protein; [O] COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.
   
 0.934
EED31647.1
ATPase; [S] COG0316 Uncharacterized conserved protein; Belongs to the HesB/IscA family.
 
 
 0.932
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 0.909
NOR53_515
Ferredoxin; [C] COG2871 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF.
  
 0.899
EED32850.1
Reductive dehalogenase; [C] COG1600 Uncharacterized Fe-S protein.
  
 0.887
erpA
HesB/YadR/YfhF; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 
 0.879
tusD
Sulfur relay protein TusD/DsrE; [P] COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction.
    
 0.876
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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