Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32898.1Biotin-requiring enzyme domain protein; [I] COG0439 Biotin carboxylase. (902 aa)    
Predicted Functional Partners:
accC
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
0.975
EED32897.1
[I] COG0777 Acetyl-CoA carboxylase beta subunit.
 
 
 0.959
EED33121.1
[I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
 
 0.952
accA
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.920
EED31654.1
Acetyl-/propionyl-coenzyme A carboxylase alpha chain; [I] COG0439 Biotin carboxylase.
 
0.911
EED32900.1
[I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).
    
  0.852
NOR53_213
methylcrotonoyl-CoA carboxylase subunit alpha; [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase).
 
0.832
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
    
 0.773
EED32676.1
Putative methylmalonyl-CoA decarboxylasealpha-subunit; [I] COG0825 Acetyl-CoA carboxylase alpha subunit.
  
 
 0.765
EED31656.1
methylcrotonoyl-CoA carboxylase beta chain; [I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
  
 
 0.765
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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