Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_196Band 7 protein; [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs. (264 aa)    
Predicted Functional Partners:
NOR53_169
[OU] COG1585 Membrane protein implicated in regulation of membrane protease activity.
 
    0.973
ftsH
Metalloprotease (cell division protein) FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.844
EED31467.1
[C] COG2863 Cytochrome c553.
   
 
 0.832
EED34033.1
CheB methylesterase/CheR methyltransferase; [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
  
 
  0.708
hflK
HflK protein; HflC and HflK could encode or regulate a protease.
  
   
 0.644
EED33221.1
Peptidase M16 inactive domain family protein; [R] COG0612 Predicted Zn-dependent peptidases.
  
 0.542
EED31902.1
Conserved hypothetical protein; [K] COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.
  
    0.534
NOR53_603
Oxidoreductase htatip2; [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases.
   
  0.534
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  0.524
NOR53_714
Hypothetical protein; [R] COG0612 Predicted Zn-dependent peptidases; putative peptidaseM16 family.
   
 0.523
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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