Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED33275.1Hypothetical protein; [V] COG1002 Type II restriction enzyme, methylase subunits. (918 aa)    
Predicted Functional Partners:
EED33276.1
DNA helicase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
    0.973
EED33277.1
Sea11; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
  
 0.961
EED31309.1
Conserved hypothetical protein.
  
    0.906
hsdM
[V] COG0286 Type I restriction-modification system methyltransferase subunit.
  
    0.584
EED33278.1
Conserved hypothetical protein.
       0.554
EED31308.1
Putative helicase, Snf2 family; [L] COG1111 ERCC4-like helicases.
 
    0.487
EED33274.1
Hypothetical protein.
       0.435
NOR53_449
Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.
   
    0.417
NOR53_461
EcoEI R C-terminal domain protein; [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
   
    0.416
NOR53_299
Type III restriction enzyme, res subunit family; [KL] COG1061 DNA or RNA helicases of superfamily II.
  
    0.413
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (20%) [HD]