Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED32665.1[S] COG4336 Uncharacterized conserved protein; Belongs to the D-glutamate cyclase family. (263 aa)    
Predicted Functional Partners:
EED32663.1
Conserved hypothetical protein TIGR00370; [E] COG2049 Allophanate hydrolase subunit 1.
 
    0.979
NOR53_756
Regulator of kinase autophosphorylation inhibitor; [E] COG1984 Allophanate hydrolase subunit 2.
 
    0.971
EED32664.1
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
 
    0.961
EED32661.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
     0.950
EED32660.1
D-alanine aminotransferase; [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
 
     0.843
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.802
EED32111.1
Transcriptional regulator, IclR-family; [K] COG1414 Transcriptional regulator.
  
    0.674
NOR53_966
Conserved hypothetical protein.
       0.513
EED32666.1
[IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
       0.451
EED32402.1
Manganese/divalent cation transport protein (nramp); [ER] COG0591 Na+/proline symporter.
  
  
 0.420
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (24%) [HD]