STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED33828.1Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (321 aa)    
Predicted Functional Partners:
EED33826.1
Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
 
     0.594
EED33827.1
[I] COG1960 Acyl-CoA dehydrogenases.
 
    0.588
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
       0.553
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
     
 0.482
EED31464.1
[L] COG2818 3-methyladenine DNA glycosylase.
  
     0.439
EED32820.1
Amino acid-binding ACT domain protein; [E] COG2716 Glycine cleavage system regulatory protein.
  
 
  0.424
EED33830.1
Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases.
       0.409
NOR53_966
Conserved hypothetical protein.
  
     0.404
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (20%) [HD]