Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32653.12-nitropropane dioxygenase, NPD; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. (322 aa)    
Predicted Functional Partners:
EED33736.1
2-nitropropane dioxygenase, NPD; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase.
  
  
  0.787
msrA-2
Peptide methionine sulfoxide reductase MsrA 2; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
    0.727
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
    
  0.612
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.588
fabK
trans-2-enoyl-ACP reductase II; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase.
  
  
 
0.585
fabD
[I] COG0331 (acyl-carrier-protein) S-malonyltransferase.
  
 
 0.579
EED32654.1
Transcriptional regulatory protein; [K] COG1695 Predicted transcriptional regulators.
       0.552
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.538
coxB
Cytochrome-c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
     
  0.524
NOR53_272
[I] COG1960 Acyl-CoA dehydrogenases.
  
 
  0.509
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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