STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED33826.1Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (162 aa)    
Predicted Functional Partners:
EED33827.1
[I] COG1960 Acyl-CoA dehydrogenases.
       0.773
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.610
ligK_1
4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; [H] COG0684 Demethylmenaquinone methyltransferase.
  
   
 0.597
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
 
     0.594
EED33828.1
Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
     0.594
ligK_2
4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; [H] COG0684 Demethylmenaquinone methyltransferase.
  
   
 0.516
EED33880.1
Arabinose 5-phosphate isomerase; [M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains.
    
  0.442
NOR53_567
Amidohydrolase family protein; [R] COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold.
 
  
 0.421
NOR53_932
6-phosphogluconate dehydrogenase, NAD-binding protein; [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
  
  0.417
EED33830.1
Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases.
 
     0.410
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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