| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED32218.1 | EED33824.1 | NOR53_3587 | NOR53_2083 | [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2. | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | 0.606 |
| EED32218.1 | dacA | NOR53_3587 | NOR53_2702 | [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2. | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; [M] COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.736 |
| EED32218.1 | ftsI | NOR53_3587 | NOR53_1219 | [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2. | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.904 |
| EED32218.1 | mpl | NOR53_3587 | NOR53_2672 | [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.406 |
| EED32218.1 | mrdA | NOR53_3587 | NOR53_2510 | [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.931 |
| EED33824.1 | EED32218.1 | NOR53_2083 | NOR53_3587 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2. | 0.606 |
| EED33824.1 | NOR53_750 | NOR53_2083 | NOR53_750 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | [M] COG2951 Membrane-bound lytic murein transglycosylase B. | 0.599 |
| EED33824.1 | NOR53_76 | NOR53_2083 | NOR53_76 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | [GEPR] COG0477 Permeases of the major facilitator superfamily. | 0.636 |
| EED33824.1 | NOR53_921 | NOR53_2083 | NOR53_921 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | [V] COG3725 Membrane protein required for beta-lactamase induction. | 0.869 |
| EED33824.1 | anmK | NOR53_2083 | NOR53_594 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.731 |
| EED33824.1 | dacA | NOR53_2083 | NOR53_2702 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; [M] COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.663 |
| EED33824.1 | ftsI | NOR53_2083 | NOR53_1219 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.760 |
| EED33824.1 | mpl | NOR53_2083 | NOR53_2672 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.647 |
| EED33824.1 | mrdA | NOR53_2083 | NOR53_2510 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.694 |
| EED33824.1 | nadC | NOR53_2083 | NOR53_1107 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | Nicotinate-nucleotide diphosphorylase (carboxylating); [H] COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.689 |
| NOR53_750 | EED33824.1 | NOR53_750 | NOR53_2083 | [M] COG2951 Membrane-bound lytic murein transglycosylase B. | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | 0.599 |
| NOR53_750 | dacA | NOR53_750 | NOR53_2702 | [M] COG2951 Membrane-bound lytic murein transglycosylase B. | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; [M] COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.775 |
| NOR53_750 | ftsI | NOR53_750 | NOR53_1219 | [M] COG2951 Membrane-bound lytic murein transglycosylase B. | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.616 |
| NOR53_750 | mrdA | NOR53_750 | NOR53_2510 | [M] COG2951 Membrane-bound lytic murein transglycosylase B. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.667 |
| NOR53_76 | EED33824.1 | NOR53_76 | NOR53_2083 | [GEPR] COG0477 Permeases of the major facilitator superfamily. | N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. | 0.636 |