STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED33824.1N-acetyl-anhydromuramyl-L-alanine amidase AmpD; [V] COG3023 Negative regulator of beta-lactamase expression. (168 aa)    
Predicted Functional Partners:
NOR53_921
[V] COG3725 Membrane protein required for beta-lactamase induction.
  
  
 0.829
dacA
D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; [M] COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
  
 0.676
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); [H] COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
  
  
 0.607
anmK
anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
  
   
 0.573
NOR53_612
[R] COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases.
  
  
 0.550
EED33822.1
Transcriptional regulator, Fis family; [KE] COG3283 Transcriptional regulator of aromatic amino acids metabolism.
       0.486
EED33821.1
Protein kinase; [RTKL] COG0515 Serine/threonine protein kinase.
       0.475
mpl
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
  
   
 0.440
NOR53_750
[M] COG2951 Membrane-bound lytic murein transglycosylase B.
     
 0.439
NOR53_76
[GEPR] COG0477 Permeases of the major facilitator superfamily.
 
   
 0.422
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.