Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED33227.1D-aminoacylase domain protein; [F] COG0044 Dihydroorotase and related cyclic amidohydrolases. (542 aa)    
Predicted Functional Partners:
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
  
  0.870
EED31692.1
[F] COG0044 Dihydroorotase and related cyclic amidohydrolases.
  
     0.714
EED33229.1
Conserved hypothetical protein; [S] COG3949 Uncharacterized membrane protein.
 
     0.642
NOR53_136
Molydopterin dinucleotide-binding region; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
  0.639
EED31452.1
Oxidoreductase, molybdopterin-binding; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
  0.639
EED33228.1
[V] COG2367 Beta-lactamase class A.
 
     0.606
fghA
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
     
  0.511
EED31826.1
Glyoxylate reductase; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
  0.511
EED33226.1
Aldolase, class II; [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.
       0.471
EED34056.1
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; [R] COG0388 Predicted amidohydrolase.
     
  0.454
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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