Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rimI[R] COG0456 Acetyltransferases. (156 aa)    
Predicted Functional Partners:
EED32404.1
Conserved hypothetical protein.
       0.796
EED32406.1
Hypothetical protein.
       0.758
argD
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
    
 0.695
EED32403.1
[R] COG1216 Predicted glycosyltransferases.
       0.687
argA_1
Amino-acid N-acetyltransferase; [E] COG1246 N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family. ArgA subfamily.
    
 0.618
EED31331.1
Transcriptional regulator, XRE family; [K] COG1396 Predicted transcriptional regulators.
  
 
 0.578
EED31222.1
GCN5-related N-acetyltransferase; [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.
   
 
 0.577
EED32402.1
Manganese/divalent cation transport protein (nramp); [ER] COG0591 Na+/proline symporter.
       0.490
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
      
 0.474
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
  
  
 0.441
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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