Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED33078.1Conserved hypothetical protein. (105 aa)    
Predicted Functional Partners:
EED31931.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.671
NOR53_323
Transcription antitermination protein NusG; [S] COG3748 Predicted membrane protein.
  
     0.577
EED32721.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.538
fecA
[P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
  
     0.521
EED32987.1
Conserved hypothetical protein.
  
     0.520
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.516
NOR53_803
[T] COG3103 SH3 domain protein; putative SH3type 3 domain protein taxon:351348.
  
     0.516
EED33076.1
Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
       0.511
EED31877.1
Conserved hypothetical protein TIGR02449; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.503
NOR53_64
[S] COG5481 Uncharacterized conserved small protein containing a coiled-coil domain.
  
     0.493
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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