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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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queDQueuosine biosynthesis protein QueD; [H] COG0720 6-pyruvoyl-tetrahydropterin synthase. (117 aa)    
Predicted Functional Partners:
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.990
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.965
EED32834.1
NADPH-dependent 7-cyano-7-deazaguanine reductase (nadph-dependent nitrile oxidoreductase); [R] COG0780 Enzyme related to GTP cyclohydrolase I.
  
  
 0.904
folE_2
[H] COG0302 GTP cyclohydrolase I.
  
 
 0.826
folE_1
[H] COG0302 GTP cyclohydrolase I.
  
 
 0.826
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
 
 0.708
EED32426.1
[H] COG0720 6-pyruvoyl-tetrahydropterin synthase.
    
  0.650
EED33300.1
[P] COG3540 Phosphodiesterase/alkaline phosphatase D.
     
  0.647
EED31774.1
[P] COG1785 Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.647
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
     
 0.584
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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