Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hmuTHemin ABC transporter, periplasmic hemin-binding protein; [P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. (273 aa)    
Predicted Functional Partners:
EED33982.1
[P] COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 0.989
EED32627.1
Hemin import ATP-binding protein HmuV; [G] COG1129 ABC-type sugar transport system, ATPase component.
 
 
 0.983
EED33981.1
Hemin import ATP-binding protein HmuV; [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.
 
 
 0.978
hmuU
Hemin ABC transporter, permease protein; [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 0.956
EED33984.1
TonB-dependent heme/hemoglobin receptor family protein; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
 
  
 0.864
hutZ
Heme-binding protein HutZ; [P] COG0748 Putative heme iron utilization protein.
 
  
 0.702
EED33985.1
Conserved hypothetical protein; [P] COG3721 Putative heme iron utilization protein.
 
  
 0.657
EED31858.1
Periplasmic protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
  
 0.585
NOR53_698
[P] COG2375 Siderophore-interacting protein.
 
    0.485
EED33369.1
[P] COG2375 Siderophore-interacting protein.
 
    0.458
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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