Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED33752.1Acetyltransferase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (324 aa)    
Predicted Functional Partners:
EED33751.1
[K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.773
NOR53_987
Conserved hypothetical protein.
    
   0.684
EED33750.1
Hypothetical protein.
       0.645
EED33753.1
Polysaccharide biosynthesis protein; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases.
       0.594
polA
DNA polymerase I superfamily protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
      
 0.577
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
    
 
 0.476
NOR53_182
[L] COG2925 Exonuclease I.
  
 
 
 0.462
NOR53_692
DNA internalization-related competence protein ComEC/Rec2; [R] COG0658 Predicted membrane metal-binding protein.
     
 0.431
NOR53_875
Glycosyl transferase, group 4 family protein; [M] COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.
  
    0.426
EED32307.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.424
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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