STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilFType IV pilus biogenesis/stability protein PilW; [R] COG0457 FOG: TPR repeat. (256 aa)    
Predicted Functional Partners:
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.851
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
  
    0.804
EED32223.1
Type IV pilus secretin PilQ; [U] COG4964 Flp pilus assembly protein, secretin CpaC.
  
  
  0.771
EED32053.1
[S] COG1652 Uncharacterized protein containing LysM domain.
  
     0.752
EED32221.1
Type 4 fimbrial biogenesis protein PilO; [NU] COG3167 Tfp pilus assembly protein PilO.
  
   
 0.751
EED32220.1
[NU] COG3166 Tfp pilus assembly protein PilN.
  
   
 0.746
EED32222.1
[NU] COG3168 Tfp pilus assembly protein PilP.
  
   
 0.745
EED32219.1
[NU] COG4972 Tfp pilus assembly protein, ATPase PilM.
  
   
 0.720
EED33004.1
[NU] COG3215 Tfp pilus assembly protein PilZ.
  
   
 0.668
EED31684.1
Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase.
     
 0.616
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.