Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32639.1Protein containing DUF88; [S] COG1432 Uncharacterized conserved protein. (254 aa)    
Predicted Functional Partners:
napA_1
[P] COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain.
       0.675
EED32230.1
Putative methyltransferase; [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase.
  
  
 0.582
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.582
NOR53_962
[S] COG2983 Uncharacterized conserved protein; Belongs to the UPF0260 family.
       0.571
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.454
EED32637.1
Sulphate transporter; [P] COG0659 Sulfate permease and related transporters (MFS superfamily).
       0.444
EED32636.1
UspA; [T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins.
       0.444
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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