STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED33400.1Nucleoprotein/polynucleotide-associated enzyme; [S] COG3122 Uncharacterized protein conserved in bacteria. (218 aa)    
Predicted Functional Partners:
EED31876.1
[S] COG3079 Uncharacterized protein conserved in bacteria; Belongs to the UPF0149 family.
  
     0.604
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
     0.589
hflD
Conserved hypothetical protein; [R] COG2915 Uncharacterized protein involved in purine metabolism.
  
     0.511
EED33398.1
Fatty acyl-CoA hydrolase, medium chain (Thioesterase B); [I] COG0657 Esterase/lipase; Belongs to the type-B carboxylesterase/lipase family.
       0.506
icd_2
Isocitrate dehydrogenase, NADP-dependent; [C] COG0538 Isocitrate dehydrogenases.
       0.506
NOR53_390
HAD-superfamily hydrolase subfamily IA, variant 3; [R] COG0637 Predicted phosphatase/phosphohexomutase.
  
     0.493
EED33239.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
     0.455
rnt
Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.
  
     0.441
EED31937.1
[F] COG0194 Guanylate kinase.
  
     0.415
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.