Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED33930.1Conserved hypothetical protein. (320 aa)    
Predicted Functional Partners:
EED33929.1
Hypothetical protein.
       0.773
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 
  0.743
EED31511.1
[O] COG0386 Glutathione peroxidase; Belongs to the glutathione peroxidase family.
     
  0.743
hepA
RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
    
  0.604
EED31275.1
Putative helicase; [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family.
    
  0.604
EED32250.1
Type III restriction enzyme, res subunit family; [LKJ] COG0513 Superfamily II DNA and RNA helicases.
    
  0.604
EED32263.1
Methyltransferase domain family protein; [R] COG0457 FOG: TPR repeat.
   
  0.562
EED32518.1
Transporter; [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
    
  0.540
EED32517.1
Von Willebrand factor, type A; [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
    
  0.540
EED33197.1
TPR repeat-containing protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
    
  0.540
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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