Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32733.16-phosphogluconate dehydrogenase, NAD-binding; [G] COG0362 6-phosphogluconate dehydrogenase. (298 aa)    
Predicted Functional Partners:
EED32734.1
[E] COG1362 Aspartyl aminopeptidase.
       0.786
uppP
Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
 
     0.771
NOR53_898
Peptidase M22, glycoprotease; [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.
       0.742
EED31826.1
Glyoxylate reductase; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.736
mmsB
[G] COG1023 Predicted 6-phosphogluconate dehydrogenase; Belongs to the HIBADH-related family.
  
  
 
0.716
EED32502.1
Alcohol dehydrogenase, zinc-binding domain protein; [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.
  
  
  0.703
gltA
[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.664
EED33695.1
Putative aminotransferase class III (putative 4-aminobutyrate aminotransferase); [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.647
NOR53_195
Conserved hypothetical protein; [H] COG1072 Panthothenate kinase.
     
  0.647
mmsA
Methylmalonate-semialdehyde dehydrogenase; [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.
  
 
 0.640
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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