Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ttcAPyridoxamine 5'-phosphate oxidase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (281 aa)    
Predicted Functional Partners:
EED31817.1
Aminotransferase, class V; [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
    0.917
petB
ubiquinol-Cytochrome c reductase, cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
  0.902
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.810
ccmB
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
       0.803
ccmA_1
Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
       0.803
dsrH
Sulfur relay protein TusB/DsrH.
     
 0.768
EED31467.1
[C] COG2863 Cytochrome c553.
    
  0.766
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
    
  0.740
EED32603.1
Cysteine desulfurase; [R] COG1103 Archaea-specific pyridoxal phosphate-dependent enzymes.
    
 0.704
dndA
Cysteine desulfurase DndA; [E] COG0520 Selenocysteine lyase.
    
 0.704
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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