Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
galE_1UDP-glucose 4-epimerase; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (343 aa)    
Predicted Functional Partners:
galT
[C] COG1085 Galactose-1-phosphate uridylyltransferase.
  
 0.994
EED33429.1
Galactokinase; [I] COG1577 Mevalonate kinase; Belongs to the GHMP kinase family. GalK subfamily.
 
 0.991
NOR53_57
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [G] COG0662 Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 
 0.934
galU
UTP-glucose-1-phosphate uridylyltransferase; [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).
 
  
 0.903
EED32554.1
Udp-glucose 6-dehydrogenase; [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase.
  
 
 0.878
EED31331.1
Transcriptional regulator, XRE family; [K] COG1396 Predicted transcriptional regulators.
  
 
 0.823
NOR53_818
NAD-dependent epimerase/dehydratase; [M] COG1088 dTDP-D-glucose 4,6-dehydratase.
 
 
0.805
rfbB
dTDP-glucose 4,6-dehydratase; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
 
 0.802
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
   
 0.769
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
    
 0.743
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.