Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32479.1[V] COG1680 Beta-lactamase class C and other penicillin binding proteins. (420 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
       0.533
EED33256.1
Thiamine pyrophosphate enzyme domain protein TPP-binding protein; [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].
  
     0.506
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.469
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
 0.451
EED33405.1
Sn-glycerol-3-phosphate import ATP-binding protein UgpC 1; [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.
     
  0.430
EED33404.1
Sn-glycerol-3-phosphate import ATP-binding protein UgpC 3; [G] COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.
     
  0.430
EED33406.1
[G] COG1175 ABC-type sugar transport systems, permease components.
     
  0.400
EED32477.1
Ggef/eal/pas/pac-domain containing protein; [T] COG2202 FOG: PAS/PAC domain.
       0.400
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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