STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hflDConserved hypothetical protein; [R] COG2915 Uncharacterized protein involved in purine metabolism. (209 aa)    
Predicted Functional Partners:
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.959
EED32905.1
Cupin 4 family protein; [S] COG2850 Uncharacterized conserved protein.
 
  
 0.721
purB
Adenylosuccinate lyase; [C] COG0114 Fumarase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
    0.707
rnt
Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.
  
    0.676
NOR53_920
Acetyltransferase, GNAT family; [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
       0.632
EED33096.1
[S] COG3100 Uncharacterized protein conserved in bacteria.
  
    0.611
EED32909.1
Ribosomal large subunit pseudouridine synthase E; [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.
       0.610
zipA
ZipA, C-terminal FtsZ-binding domain; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
     0.608
EED33014.1
Conserved hypothetical protein; [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein.
  
    0.601
NOR53_101
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.571
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.