STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED33212.12-dehydropantoate 2-reductase; [H] COG1893 Ketopantoate reductase. (341 aa)    
Predicted Functional Partners:
NOR53_891
Creatininase; [R] COG1402 Uncharacterized protein, putative amidase.
 
     0.936
EED33211.1
Dehydrogenase/reductase sdr family member 4; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
     0.866
alkB
[L] COG3145 Alkylated DNA repair protein.
   
    0.584
panE_2
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
     0.535
NOR53_727
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
    0.535
EED33215.1
Conserved hypothetical protein.
       0.497
EED33210.1
[I] COG1960 Acyl-CoA dehydrogenases.
       0.459
NOR53_911
[I] COG1960 Acyl-CoA dehydrogenases.
       0.454
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.446
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.446
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.