Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (493 aa)    
Predicted Functional Partners:
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 
 0.998
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
 
 
 0.993
glk_1
Glucokinase; [G] COG0837 Glucokinase; Belongs to the bacterial glucokinase family.
 
 
 0.981
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.962
EED33441.1
Khg/kdpg aldolase; [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.
 
  
 0.956
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
 
 
 0.940
pgi
[G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.935
glk_2
Glucokinase/transcriptional regulator, RpiR family, fusion; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation.
 
  
 0.913
pyk
[G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.872
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
 
 0.847
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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