| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED32186.1 | nadD | NOR53_3054 | NOR53_2825 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.647 |
| EED32186.1 | nadE | NOR53_3054 | NOR53_149 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.746 |
| EED32186.1 | nadK | NOR53_3054 | NOR53_2386 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.853 |
| EED32186.1 | pntA | NOR53_3054 | NOR53_3475 | Oxidoreductase; [C] COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD(P) transhydrogenase, alpha subunit; [E] COG0686 Alanine dehydrogenase. | 0.998 |
| EED33199.1 | EED33201.1 | NOR53_1320 | NOR53_1023 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Rhomboid family protein; [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | 0.743 |
| EED33199.1 | NOR53_771 | NOR53_1320 | NOR53_771 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | [S] COG3139 Uncharacterized protein conserved in bacteria. | 0.852 |
| EED33199.1 | nadK | NOR53_1320 | NOR53_2386 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.773 |
| EED33199.1 | pepN | NOR53_1320 | NOR53_1198 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | [E] COG0308 Aminopeptidase N. | 0.785 |
| EED33201.1 | EED33199.1 | NOR53_1023 | NOR53_1320 | Rhomboid family protein; [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.743 |
| EED33201.1 | NOR53_771 | NOR53_1023 | NOR53_771 | Rhomboid family protein; [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | [S] COG3139 Uncharacterized protein conserved in bacteria. | 0.841 |
| EED33201.1 | nadK | NOR53_1023 | NOR53_2386 | Rhomboid family protein; [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.822 |
| EED33201.1 | pepN | NOR53_1023 | NOR53_1198 | Rhomboid family protein; [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | [E] COG0308 Aminopeptidase N. | 0.689 |
| EED33454.1 | nadE | NOR53_2282 | NOR53_149 | Putative Phosphate acetyl/butyryl transferase subfamily; [C] COG0281 Malic enzyme. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.792 |
| EED33454.1 | nadK | NOR53_2282 | NOR53_2386 | Putative Phosphate acetyl/butyryl transferase subfamily; [C] COG0281 Malic enzyme. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.775 |
| NOR53_771 | EED33199.1 | NOR53_771 | NOR53_1320 | [S] COG3139 Uncharacterized protein conserved in bacteria. | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.852 |
| NOR53_771 | EED33201.1 | NOR53_771 | NOR53_1023 | [S] COG3139 Uncharacterized protein conserved in bacteria. | Rhomboid family protein; [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | 0.841 |
| NOR53_771 | nadK | NOR53_771 | NOR53_2386 | [S] COG3139 Uncharacterized protein conserved in bacteria. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.747 |
| NOR53_771 | pepN | NOR53_771 | NOR53_1198 | [S] COG3139 Uncharacterized protein conserved in bacteria. | [E] COG0308 Aminopeptidase N. | 0.785 |
| cinA | nadD | NOR53_194 | NOR53_2825 | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.923 |
| cinA | nadE | NOR53_194 | NOR53_149 | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.922 |
