Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EED31422.1[GEPR] COG0477 Permeases of the major facilitator superfamily. (396 aa)    
Predicted Functional Partners:
acdS
Short-chain dehydrogenase/reductase family; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.773
EED31420.1
Hypothetical protein.
       0.625
hom
[E] COG0460 Homoserine dehydrogenase.
   
  0.552
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.527
EED33765.1
P-protein; [E] COG1605 Chorismate mutase.
   
 
 0.489
EED31772.1
Acyltransferase family protein; [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
     
  0.458
carA
Carbamoyl-phosphate synthase, small subunit; [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II; Belongs to the CarA family.
       0.456
carB
Carbamoyl-phosphate synthase, large subunit; [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; Belongs to the CarB family.
       0.456
greA
GreA/GreB family elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.443
EED33552.1
Putative multidrug resistance protein; [M] COG0845 Membrane-fusion protein.
   
 0.437
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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